Retinal Vein Occlusion

Overview of branch retinal vein occlusion and central retinal vein occlusion.

What is a Retinal Vein Occlusion?

Arteries bring blood to the eye and veins bring blood back to the heart. While arteries have tough walls which usually become harder with age, veins have thin walls which remain pliant and soft throughout life. Because of the anatomy of the eye, the retinal veins are prone to occlusion. There are two main locations where retinal veins are occluded. One is at the crossing of a retinal arteriole and branch retinal vein. An occlusion at a crossing of a branch retinal arteriole and branch retinal vein causes a branch retinal vein occlusion. The second is at the main trunk of the retinal vein where it leaves the eye through the optic nerve. An occlusion at the main trunk of the retinal vein causes a central retinal vein occlusion. The picture shows a photo with dilated veins and retinal hemorrhages from a fresh central retinal vein occlusion.

What is a Branch Retinal Vein Occlusion?

A branch retinal vein occlusion occurs when, because of hardening of the arteries, a branch retinal artery compresses a branch retinal vein causing blockage of the vein and decreased circulation in the distribution of that branch retinal vein. (see image) [note: the branch arteries are really arteriols and the branch veins are really veinules] There are several possible treatments for branch retinal vein occlusion including intravitreal injections, laser, and even surgery. Patients with BRVO lose vision for several reasons: poor circulation, hemorrhage and macular edema (swelling). There is no treatment, at the moment, to increase circulation or to remove hemorrhage. The macular edema, however, does respond well to intravitreal injections with Lucentis, Avastin, or steroids.

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What is a Central Retinal Vein Occlusion?

The inner layers of the retina receive their blood supply from the central retinal artery. The blood returns to the heart through the central retinal vein. Both vessels enter the eye through a small opening in the middle of the optic nerve. Either because this opening shrinks or because the artery hardens or because of circulations problems, the central retinal vein can become partially or completely occluded. When a patient develops a central retinal vein occlusion (CRVO), they lose some or most of their central vision. The retinal veins dilate and their are retinal hemorrhages. Patients often develop swelling of the central retina-cystoid macular edema--causing some of the vision loss. Without treatments, 25% of eyes improve, 50% stabilize, and 25% worsen. Monthly examinations of pateints with CRVO for less than six months are very important. Some patients with CRVO and very bad circulation, develop a severe type of glaucoma. In this situation, the eye becomes red and painful and without treatment, total visual loss can occur rapidly. If an examining doctor sees early signs that this complication may occur, then laser treatment can sometimes protect the eye. Once the pressure rise occurs, surgery can be helpful.

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Retinal Vein Occlusion NEWS

Below are current articles from a Google News Feed on Retinal Vein Occlusion

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Morphological Implications of Vascular Structures Not Visualized on Optical Coherence Tomography Angiography in ...
Healio
From the Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago. This research was presented at the Association for Research in Vision and Ophthalmology annual meeting in March 2017. The authors report no relevant ...


Retinal Vein Occlusion: H1 2018 Pipeline Review Report - ResearchAndMarkets.com
Odessa American
Retinal Vein Occlusion - Pipeline Review, H1 2018, provides comprehensive information on the therapeutics under development for Retinal Vein Occlusion (Ophthalmology), complete with analysis by stage of development, drug target, mechanism of action ...


Early VA gain predictive of visual response after dexamethasone treatment
Healio
Early visual acuity gain of 10 or more letters was predictive of a sustained response at 24 months after intravitreal dexamethasone treatment of macular edema in patients with retinal vein occlusion, according to a study. The 24-month, retrospective, ...


Clearside Biomedical Announces Completion of Patient Enrollment in First of Two Phase 3 Clinical Trials of CLS-TA in ...
GlobeNewswire (press release)
RVO is a particularly aggressive eye disease resulting from an occlusion in a vein carrying blood out of the retina. This blockage can lead to the rapid onset of symptoms, including sudden declines in vision. SAPPHIRE, a multicenter, multi-country ...


Retinal Vein Occlusion Market Analysis Revealing Key Drivers & Growth Trends through 2023
Medgadget (blog)
Retinal vein occlusion (RVO) is a common vascular disorder of the retina and one of the most common causes of vision loss worldwide. However, it is the second most common cause of vision loss from retinal vascular disease after diabetic retinopathy.

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Clearside Bio completes enrollment in late-stage study of CLS-TA in retinal vein occlusion
Seeking Alpha
Clearside Biomedical (NASDAQ:CLSD) has completed the enrollment of 460 subjects in a Phase 3 clinical trial, SAPPHIRE, assessing the combination suprachoroidal CLS-TA (triamcinolone acetonide) and Regeneron Pharmaceuticals' EYLEA (aflibercept) ...

and more »

Retinal Vein Occlusion - Pipeline Insight, 2018 Market Report; Launched via MarketResearchReports.com
Digital Journal
Market Research Reports, Inc. has announced the addition of “Retinal Vein Occlusion - Pipeline Insight, 2018” research report to their website www.MarketResearchReports.com. This press release was orginally distributed by SBWire. Lewes, DE -- (SBWIRE) ...
Global and China Retinal Vein Occlusion Therapeutics Market 2018 : Healthcare and Clinical Reviews by Expert 2023Truthful Observer
Retinal Vein Occlusion Therapeutics Market 2025: Technology Progress, Risk, Substitutes Threat and Technology ...The Financial

all 4 news articles »

Retinal Vein Occlusion - Pipeline Review, H1 2018 Market Report; Launched via MarketResearchReports.com
Digital Journal
Market Research Reports, Inc. has announced the addition of “Retinal Vein Occlusion - Pipeline Review, H1 2018” research report to their website www.MarketResearchReports.com. This press release was orginally distributed by SBWire. Lewes, DE ...


GEOPOLMonitor

Retinal Vein Occlusion Market: Identify and Understand Important and Diverse types of Therapeutics
GEOPOLMonitor
Retinal Vein Occlusion Market Pipeline Review, H1 2018, latest report provides report provides a snapshot of the global therapeutic landscape of Retinal Vein Occlusion, Key players involved with pipeline review and targeted therapeutics covering drugs ...


IOP spikes more likely after treatment in certain patients
Healio
Mild to moderate IOP spikes were seen after multiple injections of Ozurdex for treatment of uveitis, diabetic macular edema and retinal vein occlusion, but frequency of IOP spikes above 30 mm Hg did not increase, according to a study. Researchers ...


chemicalreport24.com

Global Retinal Vein Occlusion Therapeutics market Research Analysis and Growth Forecast by Manufacturers ...
chemicalreport24.com
The document on the Global “Retinal Vein Occlusion Therapeutics Market” presents elaborated advantage on the Retinal Vein Occlusion Therapeutics market. Constituents like dominating corporations, classification, dimension, business surroundings, SWOT ...


Brooks in Beta (press release) (blog)

Global Retinal Vein Occlusion Therapeutics Market 2018 Outlook – Acucela Inc, Addmedica SAS, Aerpio Therapeutics ...
Brooks in Beta (press release) (blog)
Global Retinal Vein Occlusion Therapeutics Market 2018 is a comprehensive, professional report delivering market research data that is relevant for new market entrants or established players. The research study covers significant data which makes the ...

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Data Analysis News

The Analysis of Retinal Vein Occlusion Therapeutics Market Data 2018-2025 Formycon AG, Graybug Vision Inc, Kala ...
Data Analysis News
Detailed market study on the “Global Retinal Vein Occlusion Therapeutics Market” Research Report 2018-2025 By QY Research Store. It analyses the important factors of the Retinal Vein Occlusion Therapeutics market based on present industry situations, ...


World Cup health warning for football fans
Star2.com
One study noted an explosion during the 2014 World Cup in cases of “retinal vein occlusion” – a blockage of small veins in the eye that is also known as an “eye stroke”. A common cause of vision loss, it is more common in people with cardiovascular ...

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CBC.ca

28 new drugs added to provincial formulary
CBC.ca
Islanders will now have coverage for anti-vascular endothelial growth factor (VEGF) drugs for three additional eye conditions including diabetic macular edema, macular edema due to retinal vein occlusion, and choroidal neovascularisation. The province ...


Find Market Research By Abhishek Budholiya (press release) (blog)

Retinal Vein Occlusion Therapeutics Market to Hold a High Potential for Growth by 2021
Find Market Research By Abhishek Budholiya (press release) (blog)
Retinal vein occlusion (RVO) is one of the major cause of visual loss among the geriatric population. RVO is the second common cause of blindness after diabetic retinopathy. The RVO is mainly of two types based on the anatomy of the vein occlusion.


High Purity Tin Telluride Market 2018 to 2023, By Industry Overview, Opportunities, In-Depth Analysis with Top Key ...
The Financial
“Global Retinal Vein Occlusion Therapeutics Market” is estimated to grow at a rapid pace during the period of 2018-2023. This market is segmented by Retinal Vein Occlusion Therapeutics types, applications, and Retinal Vein Occlusion Therapeutics market ...

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Retinal Vein Occlusion Market Report 2027 for Emerging Business Strategies in Present Research
News Publicist
Retinal Vein Occlusion – Market Insights, Epidemiology and Market Forecast – 2027 report gives a Comprehensive study of the Retinal Vein Occlusion, diagnosed patterns, treatment trends, unmet medical needs and current developments, the study of ...

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Retinal Vein Occlusion Therapeutics Market Insights June 2018 covering Market Share, Market Concentration Rate ...
satPRnews (press release)
In this report the Global Retinal Vein Occlusion Therapeutics Market is valued (valuation provided in sample report) million in 2018 and is expected to reach USD (forecast provided in sample report) million by end of 2025, growing at a CAGR of ...


BLOG: Does anti-VEGF work for the cornea?
Healio (blog)
... of tumors in cases of systemic cancer, anti-VEGF medications have for years been injected into the vitreous chamber for a variety of maladies such as: exudative macular degeneration, diabetic retinopathy, cystoid macular edema and retinal vein ...


GEOPOLMonitor

Retinal Vein Occlusion Market Research Report H1: Drug Profile, Top Industry Intelligence and Therapeutic Development
GEOPOLMonitor
Retinal Vein Occlusion Market – Pipeline Review H1 2018, provides detail overview of Retinal Vein Occlusion development scenario. This report delivers top-line data relating to the Retinal Vein Occlusion Market pipeline landscape and also includes ...


thehonestanalytics.com

Cystoid Macular Edema Market Greater Revenue Share by 2025
thehonestanalytics.com
Various risk factors associated with cystoids macular edema are penetrating keratoplasty (corneal transplant), retinal surgery, chronic renal failure, retinal vein occlusion, retinitis pigmentosa, systemic medication and topical prostaglandin analogs ...

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The Business Times

Football fans, keep your eye on your health this World Cup
The Business Times
One study noted an explosion during the 2014 World Cup in cases of "retinal vein occlusion" - a blockage of small veins in the eye that is also known as an "eye stroke". A common cause of vision loss, it is more common in people with cardiovascular ...
World Cup 2018 could be your last event if you overlook serious health issues on match dayInternational Business Times, Singapore Edition

all 2 news articles »

Regeneron Pharmaceuticals Inc (REGN) Holdings Decreased by Opus Point Partners Management LLC
Macon Daily
... neovascularization; and diabetic retinopathy in patients with DME, as well as macular edema following retinal vein occlusion, including macular edema following central retinal vein occlusion and macular edema following branch retinal vein occlusion.

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International Business Times, India Edition

Oxford researchers just made a robot perform successful eye surgeries on patients
International Business Times, India Edition
KU Leuven (University of Leuven, Belgium) developed the robot and needle specifically for this procedure, known as retinal vein cannulation (RVC), a treatment that addresses the retinal vein occlusion by removing the blood clot in the retinal vein ...

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Motley Fool

Clearside Biomedical Stock Down 26%: The "Positive" Data That Wasn't
Motley Fool
Today's lackluster results may also be giving investors pause regarding upcoming data testing CLS-TA plus Eylea in patients with retinal vein occlusion, although the eye diseases are different enough that it's hard to make a firm conclusion on how much ...
Stock's Trend Analysis Report: Clearside Biomedical, Inc. (NASDAQ:CLSD), AutoNation, Inc. (NYSE:AN)The Oracle Examiner
What's Next for Clearside Biomedical, Inc. (CLSD) After Forming Bullish Double Top?Reurope

all 63 news articles »

The Guardian

UPDATE: PEI government now covers cancer drug for Valleyfield woman
The Guardian
All three of these medications are being added to the formulary for the treatment of: diabetic macular edema (DME); Macular edema due to retinal vein occlusion (RVO); Choroidal neovascularization (CNV). Liver disease. Zaxine is being added for the ...

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Opioids Market Anticipated to Garner US$ 42158.8 Mn by 2021 - Persistence Market Research
GlobeNewswire (press release)
Non-infectious Macular Edema Treatment Market Segmentation By Drug Type (Anti-VEGF, Corticosteroids, Immunosuppressant, Biologics, Others); By Indication (Non-infectious Uveitic Macular Edema, Diabetic Macular Edema, Retinal Vein Occlusion with ...

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Zacks.com

Mylan (MYL) Gets FDA Approval for Biosimilar of Neulasta
Zacks.com
Eylea, a vascular endothelial growth factor (VEGF) inhibitor, has been approved for the treatment of neovascular (wet) age-related macular degeneration, macular edema, following retinal vein occlusion, diabetic macular edema and diabetic retinopathy in ...

and more »

The Daily Star

Football fans: World Cup health warning
The Daily Star
One study noted an explosion during the 2014 World Cup in cases of "retinal vein occlusion" -- a blockage of small veins in the eye that is also known as an "eye stroke". A common cause of vision loss, it is more common in people with cardiovascular ...

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