Age Related Macular Degeneration

AMD has two forms - wet and dry. Below is an overview of wet and dry AMD

What is the Macula?

The macula is the center part of the retina that we look straight ahead with. The eye works like a camera. The retina is like the film in the back of a camera. The center of the retina is called the macula. When you look at someone's face or read a book, you are using your macula. That is where your fine vision is. The rest of the retina is for the side or peripheral vision. You cannot see well with your peripheral vision, but you can get around and function with your peripheral vision. Macular degeneration can cause central vision loss, but never causes loss of peripheral vision (side vision).

What is Dry Macular Degeneration?

Dry AMD occurs when drusen develop in the macula (see photo). Most people with dry AMD have normal or near normal vision. Only about 10 percent develop advanced dry AMD. Advanced dry AMD occurs when the retina thins out so much that the vision declines. We call the thin spots geographic atrophy. We recommend vitamins for patients with dry AMD and fish oil. Patient with dry AMD should follow their vision and amsler grid every day and report to their physician if their is a change in vision in either eye or a change on the amsler grid. It is very important to check each eye separately.

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What is Wet Macular Degeneration?

Wet AMD occurs when blood vessels start to grow in the macula. These blood vessels can also grow with scar tissue and blood (see photo). Untreated, most people with wet AMD lose their central vision. With treatment, the disease progression can usually be stopped and often reversed. Promt treatment leads to the best results, so if you have a sudden change in vision that could be a sign of wet AMD, you should see your physician urgently.

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Macular Degeneration NEWS

Below are current articles from a Google News Feed on Macular Degeneration

What is age-related macular degeneration?  Times Herald-Record

February is Age-Related Macular Degeneration (AMD) Month.Age-related macular degeneration is deterioration of the retina and deeper layers of the eye that ...

Bowie woman's increasing blindness from macular degeneration depicted in film  Times Record News

Macular degeneration is the leading cause of vision loss affecting more than 10 million Americans, more than cataracts and glaucoma combined.

7 Tips to Stop Macular Degeneration  Healthline

Macular degeneration is one of the leading causes of blindness in the United States. Here's how to keep your vision safe while enjoying the sun this spring ...

Seeing clearly: Know your risk for macular degeneration  Baylor College of Medicine News

More than 60 million Americans are estimated to be at high risk for vision loss. However, according to the CDC, only half of those at risk have visited an eye ...

Ask a Doctor: Is macular degeneration hereditary?  Chattanooga Times Free Press

Q: A family member has macular degeneration. Will I get it? A: Age-related macular degeneration is the most common cause of vision loss in people over age 50 ...

Alzheimer's Q&A: Is there a link between age-related macular degeneration and Alzheimer's disease?  The Advocate

Age-related macular degeneration is a common eye condition and also a leading cause of vision loss among those 50 and older. The condition causes damage ...

Macular degeneration treatment market size worth around US $11.4 billion by 2026: Acumen Research and Consulting  GlobeNewswire

LOS ANGELES, March 16, 2019 (GLOBE NEWSWIRE) -- The global macular degeneration treatment market size is anticipated to value USD 11.4 billion by ...

Macular Degeneration Treated with Viral Delivery of Gene Into Eye |  Medgadget

A number of degenerative eye diseases are related to photoreceptors no longer functioning properly. There can be a host of reasons that photoreceptors.

Age-related Macular Degeneration - Worldwide Partnering Overview, 2012 to 2018 (2019 Update): Trends in Partnering Deals, Top Deals by Value -  Associated Press

This *content* is a press release from our partner Business Wire. The AP newsroom and editorial departments were not involved in its creation.

Dr Joshua Dunaief MD, Renowned Age-Related Macular Degeneration Clinician and Researcher, Joins Mperia Therapeutics Inc. Clinical Advisory Board  BioSpace

MONTREAL--(BUSINESS WIRE)-- Dr. Joshua Dunaief, PhD, MD, the Adele Niessen Professor of Ophthalmology, Scheie Eye Institute, University of ...

Wet Age-Related Macular Degeneration Market to Reach $10.4 Billion by 2024: P&S Intelligence  GlobeNewswire

NEW YORK, March 11, 2019 (GLOBE NEWSWIRE) -- According to the market research report published by P&S Intelligence, global wet age-related macular ...

Extra Calcium Safe for the Aging Eye  HealthDay

FRIDAY, March 22, 2019 (HealthDay News) -- To take calcium or not to take calcium, that is still the question. In a new study that contradicts earlier research, ...

7 Macular Degeneration Risk Factors You Can Control—and 4 You Can't  Reader's Digest

Your chances of getting this top cause of vision loss in people age 60 and older—depends on both your genetics and your lifestyle.

Roche and Genentech take global macular degeneration step  PharmaTimes

Roche and Genentech have initiated two large global Phase III clinical trials testing the potential of faricimab in wet age-related macular degeneration. - News ...

Ranibizumab, Bevacizumab Associated with Five-Year AMD Visual Acuity Decline  MD Magazine

There has been a debate about whether retina specialists under-treat with anti-VEGF therapy in the real-world setting.

NIH study finds no evidence that calcium increases risk of AMD  National Institutes of Health

Eating a calcium-rich diet or taking calcium supplements does not appear to increase the risk of age-related macular degeneration (AMD), according to the ...

VisionCare, Inc. Announces Regulatory Approval of the CentraSight Treatment Program in Australia  Associated Press

This *content* is a press release from our partner Business Wire. The AP newsroom and editorial departments were not involved in its creation.

Injection Shown to Restore Sight in Mice

A simple injection has been found to restore sight in mice blind mice, providing vision good enough to distinguish objects and shapes.

Age-related macular degeneration and mortality outcomes | JAMA  MD Linx

Internal Medicine Article: Association of age-related macular degeneration with risk of all-cause and specific-cause mortality in the national health and nutrition ...

VisionCare wins approval for CentraSight implant in Australia  Medical Design & Outsourcing

VisionCare (Saratoga, Calif.) recently announced that it has received regulatory approval from the Australian Department of Health Therapeutic Goods.

How To Protect Your Vision and Avoid Macular Degeneration  Life Pulse Health

While winter weather may be keeping you indoors this February, spring break is around the corner. And if you're planning to go somewhere sunny, don't forget ...

BioTime to Present New Data From OpRegen® and Vision Restoration Programs at the Association for Research in Vision and Ophthalmology Annual Meeting (ARVO 2019)  Associated Press

This *content* is a press release from our partner Globe Newswire. The AP newsroom and editorial departments were not involved in its creation.

UC Berkeley researchers use gene therapy to restore eyesight to blind mice  KGO-TV

Researchers at UC Berkeley injected a special gene into the retina of blind mice and, within a few weeks, the mice were able to regain eyesight.

Age-Related Macular Degeneration Awareness Month: How visual impairment affects older adults

As Age-Related Macular Degeneration/Low Vision Awareness Month comes to a close, we're sharing three stories by Bonnielin Swenor, Ph.D., M.P.H., assistant ...

Implantable Miniature Telescope approved in Australia  Healio

The Australian Department of Health Therapeutic Goods Administration has issued a Therapeutic Goods Certificate to the Implantable Miniature Telescope, ...

Global Macular Degeneration Treatment Market Size, Demand Analysis, Growth Rate and Deep Industry Research Reports  openPR

Macular Degeneration Treatment Market research report 2019-2024 presents a comprehensive study of the Macular Degeneration Treatment Market in Global ...

Pixium Vision to host KOL Meeting on March 5, 2019 in Paris  GlobeNewswire

Paris, France. February 28, 2019 – 7.00 AM CET - Pixium Vision (FR0011950641 - PIX), a bioelectronics company developing innovative bionic vision systems ...

Two phase 3 trials to investigate faricimab for wet AMD  Healio

Roche and Genentech are initiating two phase 3 global trials to investigate the bispecific molecule faricimab for the treatment of wet age-related macular ...

Dear Dr. Roach: How often should healthy patients undergo eye examinations?  Herald & Review

Dear Dr. Roach: How often does a healthy person with perfect vision and no eye concerns need to see an eye doctor?

Wilmington clinic to demonstrate electronic glasses for visually impaired  Burlington Times News

A clinic to demonstrate the eSight adaptive device will be held April 12-13 at St. Paul's Lutheran Church. Advance registration is required.

Théa and OliX Announce Collaboration to Develop RNAi Therapies for the Treatment of AMD  PRNewswire

License and Collaboration Agreement was signed between OliX and Théa for OLX301A program, a novel treatment for dry and wet age-related macular ...

Machine Learning Proven Beneficial for Diagnosing, Monitoring wAMD  MD Magazine

Support vector machine learning (SVML) can be a useful tool in monitoring wet age-related macular degeneration (wAMD), proving to be as effective as retina ...

Chopped, uncooked spinach offers more antioxidants – Harvard Health  Harvard Health

Chopping uncooked spinach preserves higher amounts of the antioxidant lutein compared with cooking methods like frying, boiling, and steaming.

Apellis resumes phase 3 AMD trials after addressing safety issue  FierceBiotech

Apellis Pharmaceuticals has resumed dosing in phase 3 trials of its treatment for an advanced form of age-related macular degeneration (AMD). The resumption ...

Bowie woman featured in Medicine X Xplained series  KFDX

BOWIE (KFDX/KJTL) - Research shows not visiting an eye doctor regularly can lead to diseases like Macular Degeneration, the leading cause of vision loss.

Prevent Blindness Declares April as Women's Eye Health and Safety Month  InvisionMag

(PRESS RELEASE) CHICAGO — According to Prevent Blindness, the nation's oldest eye health and safety non-profit organization, women have higher rates of ...

Age–Related Macular Degeneration trends Archives  TechnoBleak

Age-related Macular Degeneration (AMD) is one of the major cause of visual impairment in the aged population, which is an acquired retinal disorder and ...

Therapy could improve, prolong sight in those suffering vision loss  UC Berkeley

Millions of Americans are progressively losing their sight as cells in their eyes deteriorate, but a new therapy developed by researchers at the University of ...

Blind Mice Regain Their Vision After Breakthrough Gene Therapy  Interesting Engineering

The therapy could be available within three years and could be a great option for those suffering from age-related retinal degeneration, or the loss of sight.

Alcon will officially leave Novartis on April 9 after an 8-year run. What's next?  FiercePharma

Exactly eight years into its full ownership of Alcon, Novartis will officially say goodbye to the eye care business on April 9. The spinoff follows Novartis' recent ...

UK woman has first gene therapy operation for dry AMD  BioNews

An 80-year-old woman from Oxford – Janet Osborne – has undergone the world's first gene therapy operation to target the root cause of age-related macular ...

Vision Loss Sees New Therapy through Calming Hyperactive Eye Cells  Genetic Engineering & Biotechnology News

A group of researchers from the University of California, Berkeley, is taking a new path of treatment development for eye diseases such as retinitis pigmentosa ...

Fluoride Can Cause Degenerative Eye Diseases, Study Shows  PRNewswire

NEW YORK, March 18, 2019 /PRNewswire/ -- Fluoride contributes to degenerative eye diseases such as cataracts, age related macular degeneration (AMD) ...

Blind mice regain sight; treatment could be available to humans in three years

It was surprisingly simple. University of California, Berkeley, scientists inserted a gene for a green-light receptor into the eyes of blind mice and, a.

CD11b-positive monocytes could help guide anti-VEGF treatment in CNV diseases  medwireNews

CD11b-positive monocytes guide future anti-vascular endothelial growth factor injection need in neovascular age-related macular degeneration and.

Blind mice get their sight back after gene insertion  Futurity: Research News

Injecting genes into the eyes of blind mice restored their vision, researchers say. Could people be next?

How to improve and protect eyesight naturally: 11 ways  Medical News Today

There are many natural ways a person can help protect and improve their eyesight without the need for corrective glasses. This can include simple things such ...

What Is the Difference Between Wet or Dry Macular Degeneration?  University of Michigan Health System News

Dry macular degeneration occurs when cells of the macula begin to thin and break down. It is characterized by drusen buildup and typically worsens over time.

REGENXBIO Inc. (RGNX) Plunges 7.46% on March 22

REGENXBIO Inc. is a Regenxbio Inc is a biotechnology company. Its main activity is the development and commercialization of recombinant adeno-associated ...

Outlook advancing eye disease candidate ONS-5010  Seeking Alpha

Outlook Therapeutics (OTLK -4.5%) has filed an IND with the FDA seeking sign-off to start a U.S. Phase 3 clinical trial evaluating ONS-5010 for the treatment of ...

Aerie Pharmaceuticals Initiates Phase 2 Clinical Trial of AR-1105 (Dexamethasone Intravitreal Implant) in Patients with Macular Edema Associated with Retinal Vein Occlusion  BioSpace

DURHAM, N.C.--(BUSINESS WIRE)-- Aerie Pharmaceuticals, Inc. (NASDAQ:AERI) (Aerie), an ophthalmic pharmaceutical company focused on the discovery, ...

Top News in Medical Student March 22 2019 (9 of 33)  MD Linx

Reuters Health News | March 22, 2019. Swept-source optical coherence tomography angiography (SS-OCTA) may detect eye abnormalities in patients taking ...

SENTZ, George R.  Buffalo News

SENTZ - George R. March 18, 2019; beloved husband of 69 years to Clara M. (nee Anetzberger) Sentz; dearest father of Daniel (Donna) Sentz and Gerard ...

Doctor warns of condition that can leave you in the dark  WDAM

Your eyes can offer a glimpse into your health. The Chief of Retina, Vitreous, and Diabetes at Southern Eye Center in Hattiesburg, Dr. Jaime Jimenez wants to ...

Asia-Pacific Age Related Macular Degeneration Drug Market Viewpoint, Complete Analysis By Top Players, Trends And Predictions 2018-2023  Gator Ledger

Asia-Pacific Age Related Macular Degeneration Drug Market Report Provided Full Details of Executive summary Scope of the report Research Methodology ...

Smoking can damage eyesight by age 35, study suggests  Washington Post

Smoking cigarettes has long been known for its ability to damage eyesight, on top of the harm it causes to the lungs, heart and other organs. But a new study ...

Aerie (AERI) Starts Phase II Study on Eye Candidate AR-1105

Aerie (AERI) begins dosing in a phase II study on AR-1105 for treating patients with macular edema due to retinal vein occlusion.

Intravitreal (IVT) Injectables Market is Expected to Rake in Revenues Worth US$ 4350 Mn by 2028 End  P&T Community

NEW YORK, March 14, 2019 /PRNewswire/ -- Hereditary retinal diseases is the major cause of visual loss. Macular degeneration, Diabetic Retinopathy is the ...

7 Healthy Habits to Help Prevent Macular Degeneration  University of Michigan Health System News

AMD affects the eyesight of millions. A Michigan Medicine specialist offers easy ways to help slow or prevent the disease.

Newt Gingrich: Incredible medical breakthroughs coming to cure diseases and save lives  Fox News

The world is entering the next big wave of medical and pharmaceutical breakthroughs.

Global Age Related Macular Degeneration Market Analysis By Strategic Growth Rate And Factors 2019-2024  Global Industry Journal

Market Research Explore recently published Global Age Related Macular Degeneration Market Research Report 2019 Concentrates On Restraints, ...

Take steps to prevent vision loss from macular degeneration  Buffalo News

By Judith Whitehead – Contributing Writer Age-related macular degeneration is the leading cause of blindness among older Americans but treatments have ...

SXSW: Jordan Peele & Lupita Nyong'o on the red carpet of the world premiere of "Us"  KEYE TV CBS Austin

Jordan Peele says he wants fans to be scared in his new film, "Us," the highly anticipated follow up to his first horror film "Get Out. " We were on the red carpet for ...

Intel's Response to Donald Trump's AI Executive Order  Fortune

A month ago Donald Trump issued an executive order designed to maintain America's greatness on artificial intelligence. I reviewed it unfavorably for its lack of ...

Retinal Biologics Market to Hold at 11.1% CAGR through 2028

Retinal biologics market value surpassed US$ 14.6 billion in 2018 and projected to grow at 10.7% y-o-y in 2019, as per a new FMI study. The projected growth ...

Age-Related Macular Degeneration Genes Revealed in Transcriptome Studies  GenomeWeb

A team led by National Eye Institute researchers picked out B3GLCT and BLOC1S1 as the most plausible target genes in an age-related macular degeneration ...

Protect Your Aging Eyes From Macular Degeneration | Health News  U.S. News & World Report

By Robert Preidt, HealthDay Reporter. (HealthDay). FRIDAY, Feb. 15, 2019 (HealthDay News) -- Age-related macular degeneration (AMD) is an incurable eye ...

What you need to know about wet macular degeneration  Medical Xpress

Millions of people deal with age-related macular degeneration as they get older, but many don't understand the difference between types of the condition or ...

Blue-light-blocking glasses are gaining in popularity: Here's everything you should know about them  KSRO

iStock/twinsterphotoDR. AMRIT K. KAMBOJ (NEW YORK) -- If you've recently gone shopping for a new pair of eyeglasses, there's a chance you may have come ...

Blind mice see again: Single gene therapy for human trials in three years  The New Daily

In three years time, people made blind by macular degeneration – and others with inherited retinigtis pigmentosa – may be able to navigate a cluttered Thanks ...

MacuLogix® Raises $38.7 Million in Series D

MacuLogix, Inc., a company equipping eye care professionals with the instrument, tools, and education needed to effectively diagnose and treat patients wit.

Blind Mice Regain Sight After Single Gene Insertion  Technology Networks

Technology Networks is an internationally recognised publisher that provides access to the latest scientific news, products, research, videos and posters.

Breakthrough in identifying new genes in age-related macular degeneration, the leading cause of blindness  Medical Xpress

Fight for Sight funded research published this week in Clinical Epigenetics, has identified new genes linked to the development of age-related macular ...

Research into new macular degeneration treatments takes off as cases rise  STAT

Scientists are experimenting with dozens of drug candidates, including about 20 in clinical trials, that work to preserve vision and restore sight.

Policies designed for drugs won't work for AI

Health authorities are overlooking risks to systems and society in their evaluations of new digital technologies, says Melanie Smallman.

Aged-related macular degeneration is incurable but preventable  New Jersey 101.5 FM Radio

Aged-related macular degeneration is the top cause of blindness in people age 50 and older.

Roche acquires Spark in $4.8B gene therapy play  BioPharma Dive

Roche is acquiring Spark Therapeutics in a multi-billion dollar deal that underscores big pharma's growing appetite for new technologies like gene therapy.

What is Low Vision?  CBS Baltimore

It is most common in people 60 and older, but low vision can affect anyone at any age. “Things that cause vision impairment in kids are very different than what ...

Gene Therapy for the Most Common Form of Blindness Gets Its First Human Test  Gizmodo

An 80-year-old woman from the United Kingdom is the first patient to undergo gene therapy to treat age-related macular degeneration—the most common cause ...

Macular Degeneration Patient Visual Hallucinations Associated with Retina  MD Magazine

The effects of Charles Bonnet Syndrome have been fairly documented, yet its pathology has been minimally assessed.

Public Release: 21-Feb-2019 Figuring out the fovea Harvard University Using high-throughput genetic sequencing  EurekAlert

Using high-throughput genetic sequencing methods, scientists have created the first cellular atlas of the primate retina, an important foundation for researchers ...

Age-Related Macular Degeneration: 5 Things to Know  Medscape

A guide to the latest on this chronic disease, from emerging treatments to the risk factors to be on the lookout for.

Diagnostic Efficacy and Therapeutic Decision-making Capacity of an Artificial Intelligence Platform for Childhood Cataracts in Eye Clinics: A Multicentre Randomized Controlled Trial  The Lancet

CC-Cruiser is an artificial intelligence (AI) platform developed for diagnosing childhood cataracts and providing risk stratification and treatment ...

Trial will be first in US of Nobel-winning stem cell technique  STAT

Curing diabetes with stem cells? Everyone knew that would be hard. Parkinson's disease? Harder. Alzheimer's? Probably impossible. But age-related macular ...

Antioxidants Help Improve Vision  Bel Marra Health

Antioxidants have been found to help improve vision in non-advanced age-related macular degeneration patients.

Global Age Related Macular Degeneration Drug Market will reach 8670 million US$ in 2024, from 6080 million US$ in 2019  Camping Canuck has added a new research report to its repository, titled, “Global Age Related Macular Degeneration Drug Market 2019 Industry Research ...

First human test for gene therapy targeting most common cause of blindness  Genetic Literacy Project

A woman from Oxford has become the first person in the world to have gene therapy to try to halt the most common form of blindness in the Western world.

Ophthalmology thought-leaders set sights on ARVO's annual meeting  Ophthalmology Times

More than 11,000 global thought-leaders are expected to descend upon Vancouver, BC, for the Association for Research in Vision and Ophthalmology's (ARVO) ...

Recent Fundamentals: TRACON Pharmaceuticals (NASDAQ: TCON)  Reagents Global Market

TRACON Pharmaceuticals is part of the healthcare sector and trades as part of the biotechnology industry. The company CEO is Charles P. Theuer. TRACON ...

Stem Cell Therapy Patch for Macular Degeneration Sees the Light of Day  Genetic Engineering & Biotechnology News

If approved, the first ever clinical trail to test a stem cell-based therapy may provide a cure for age-related macular degeneration.

Human Trials Could Begin for Macular Degeneration Stem Cell Therapy  MD Magazine

FDA trial approval would make this trial the first ever to test a stem cell-based therapy derived from induced pluripotent stem cells for treating any disease.

Alkahest to Present Results from Phase 2a Open Label Study of AKST4290 in wet AMD at Retina World Congress  BioSpace

Published: Mar 14, 2019. SAN CARLOS, Calif., March 14, 2019 /PRNewswire/ -- Alkahest, Inc., a clinical stage biotechnology company focused on developing ...

Treating Blindness and Vision Loss—New Technology and Possible Cures  Popular Mechanics

About 170,000 vehicles use the Queensboro Bridge each day, passing by Larry Misrok's apartment building, which sits at the entrance to one of the ramps.

Tie2 activation promotes choriocapillary regeneration for alleviating neovascular age-related macular degeneration  Science Advances

Choriocapillary loss is a major cause of neovascular age-related macular degeneration (NV-AMD). Although vascular endothelial growth factor (VEGF) blockade ...

U.Va. Hospital expands eye clinic to address the needs of a growing population  University of Virginia The Cavalier Daily

One of the main reasons for expanding the eye clinic is to improve access to care as the general populations within the Charlottesville community and across the ...

New Treatment Method to Cure Macular Degeneration  Oak Tribune

New stem cell treatment cured blindness in two patients, according to a report published on September 15, 2018.

Can vaping help you quit smoking? - Harvard Health Blog  Harvard Health

While the long-term health effects of vaping are uncertain, a recent study comparing found that it may be help some cigarette smokers quit.

Metformin for Macular Degeneration  Healthline

The popular diabetes medication, metformin, may soon be used not just to regulate blood sugar but to protect against a common form of blindness, called ...

Better assessments for early age-related macular degeneration  Medical Xpress

The European MACUSTAR consortium is conducting a multi-country clinical study on age-related macular degeneration (AMD) coordinated by the University of ...

Change Within Eye A Hint of Macular Degeneration?  WebMD

The investigators discovered that calcifications in the retina -- the thin layer of tissue that lines the back of the eye -- raise the risk of advanced age-related ...

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What about Resources?

Dr. Pautler's Blog
American Academy of Ophthalmology
National Institutes of Health
  • ARMD
    NIH's SeniorHealth website covers the topic of Age-Related Macular Degeneration
National Eye Institute
American Foundation for the Blind - Senior Site
  • Macular Degeneration
    Basic information about AMD and low vision; includes a self-test using an Amsler Grid
Journal of the American Medical Association (JAMA)
LightHouse International
  • Macular Degeneration
    Provides a general overview of the basics of AMD, and a simulation showing a scene as it might be viewed by a person with AMD
Prevent Blindness America